HEMATOLOGY
1. Hematopoiesis production of blood cells 2. Blood fx transportation - carry O2, CO2 regulate body temp, pH, electrolytes transport waste to kidney - excrete as urine protection - wbc clotting - stop internal & external bleeding 3. Component - based on density 55% plasma 1% wbc & platelet 45% rbc - Fe heavy, carry O2 4. Site yolk sac - 1-3 mth embryo liver & spleen - fetus BM - 6 mth onwards tibia femur rib sternum vertebrae 5. BM environment fats & rbc wbc red BM replace by fats - prone to anemia, aging 6. HSC self-renew multipotentiality differentiation - myeloid or lymphoid lineage 7. Surface markers identification for cells - Ag flow cytometry - cell pass laser beam, fluorescence labeled Ab detect wbc occupy BM, suppress rbc, cause anemia & thrombocytopenia 8. Cytokines/HGF regulator - protein/peptide/hormone - myeloid, lymphoid 9. Cytokines fx fx stimulat...