General Sense

General sense

Sensory receptor
  • Chemoreceptor
    • Respond to water & lipid soluble compounds 
    • Respiratory center of medulla oblongata, carotid, arteries, aortic arch 
    • Rapid adaption 
  • 3 Mechanoreceptor
    • Tactile receptor
      • Free nerve endings 
        • A fast myelinated 
        • Not in cartilage, lens 
        • Nonspecific - pain, touch, pressure, temp
        • Rapid adaption
      • Root hair plexus
        • Monitor movement of hair follicle 
        • Displacement of hair distorts sensory dendrites 
        • Generates AP
        • Rapid adaption
      • Merkel disc = tonic 
        • Large, myelinated afferent fiber
        • Fingertips, superficial skin
        • Very small receptive field
        • Pressure, touch 
        • Tactile disc + Merkel cells at basal + dendrite of single myelinated afferent fiber
        • Slow adaption
      • Meissner's
        • Large, myelinated
        • Glabrous skin, eyelid, lip, fingertip, nipple, external genitalia
        • Fine touch, low fx vibration
        • Rapid adaption 
      • Pacinian
        • Large, myelinated 
        • Finger, mammary, external genitalia, fasciae, joint capsule, viscera 
        • Pressure, high fx vibration 
        • Rapid adaption 
      • Ruffini = tonic 
        • Large, myelinated 
        • Fingertip, joint 
        • Stretch, joint angle change, pressure 
        • Slow adaption 
    • 3 Proprioceptor - recognize position, weight discrimination
      • Muscle spindle
        • Stretch reflex 
        • Muscle length
        • Slow adaption
      • Golgi tendon organs
        • Tension
        • Slow adaption
      • Joint kinesthetic receptors - rapid adaptation
        • Joint - acceleration, deceleration 
        • Rapid adaption 
    • Baroceptor 
      • Blood vessel pressure in digestive, urinary, respiratory
  • Thermoreceptor = phasic
    • Cold 3-4x warm 
    • Free nerve endings in dermis, skeletal muscle, liver
    • Initial rapid adaption 
  • Nociceptor
    • Free nerve endings everywhere not in brain
    • Fast pain: sensation reach CNS fast, A
    • Slow pain: C
    • Superficial, Deep somatic, Visceral

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